Cranberry/Cranberry – Cystitis

Cranberry is a natural remedy for urinary function and drainage of body fluids.

Natural supplement that performs a natural disinfectant of the urinary tract.

Cranberry has antiadhesive activity, hindering the adhesion of Escherichia coli and other gram negative bacteria to the walls of the intestine, bladder and urinary ducts. The anti-adhesive activity depends on the proanthocyanidins A that bind to the fimbie type P of Escherichia coli, preventing it from being attached to the urothelial mucosa.
Numerous studies have shown the effectiveness of cranberry in reducing the incidence of urinary tract infections and facilitating their resolution.
Cranberry also contains other polyphenols, resveratrol and quercetin that act as powerful antioxidants and play anti free radicals. They protect cells and tissues from oxidative stress.

It is advisable to drink plenty of water during the day to facilitate the elimination of bacteria.

Bibliography:

1. Gupta K, Chou M.Y., Howell A, et al. Cranberry products inhibit adherence of P-fimbriated Escherichia coli to
primary cultured blatter and vaginal cells. J Urol. 2007: 177, 2357-60.
2. Stothers L. A randomized trial to evaluate effectiveness and cost effectiveness of naturopathic cranberry products
as prophylaxis against urinary tract infection in women. Can J Urol. 2002;9:1558-62.
3. Fu Z, Liska D, Talan D, et al. Cranberry reduces the risk of urinary tract infection recurrence in otherwise healty
women: a systematic review and meta-analysis. J Nutr. 2017 Dec;147(12):2282-2288.
4. I. Singh, L.K. Gautam, I.R. Kaur, Effect of oral cranberry extract (standardized proanthocyanidin-A) in patients
with recurrent UTI by pathogenic E. coli: a randomized placebo-controlled clinical research study. Int. Urol. Nephrol.
2016 Sep; 48(9):1379-86.